Angela de Manzanos

Angela de Manzanos


Project: Development of a novel, generic chaperon assay to probe protein-protein AAA+ interactions: Theory and experiment in unison


Angela is studying Rubisco inefficiencies, the first enzyme in the dark phase of photosynthesis, considered a major bottleneck in photosynthesis and a promising target to increase crop yields. She started her PhD at the Institute of Chemical Biology (ICB) in Imperial College in September 2012 supervised by Dr. Laura Barter, Dr. Ian Gould and Dr. Rudiger Woscholski, partially sponsored by a Spanish charity, Obra Social Fundacion La Caixa, and by EPSRC. Angela arrived to Imperial College in September 2011 to study a Masters in Research in Chemical Biology of Crop Sustainability and Protection, at the ICB, and she was awarded with the Lord Porter Prize for her results.

Before arriving to Imperial College, Angela studied a bachelors in Biotechnology at the Polytechnic University of Valencia, Spain. During her studies in Spain she participated in research projects in Valencia, firstly studying breast cancer metastasis at the Principe Felipe Research Centre in Valencia, February 2010-September 2011 and secondly, at the Biomedicine Institute of Valencia, June-August 2009.

Angela is currently investigating Rubisco catalysis with Molecular Dynamics simulations using Amber software and she aims to elucidate Rubisco activase-Rubisco mechanisms of interaction with a combination of biophysical techniques.