Research

Daisy Rogers-Simmonds

Controlling nanopore loading in Droplet Interface Bilayers

Daisy Rogers-Simmonds - 1st year PhD

Abstract

Protein Nanopore sensing has significant potential as a next-generation sequencing methodology. In particular, our recent work has highlighted the potential for optical imaging to both parallelize nanopore recording (Huang Nat Nano 2015) and extract complementary information to the blockade of ionic current through a pore. Here, in collaboration with Oxford Nanopore Technologies (ONT), we will develop phase and compositional control of the membrane in order to manipulate the location, number, and activity of nanopores in the membrane.